Description

4'-Aminobenzo-18-Crown-6 is a functionalized crown ether derivative, specifically a benzo-18-crown-6 ether with an amino group substitution. This compound is valued for its selective ion-binding capabilities, particularly for potassium and ammonium cations, making it a critical component in phase-transfer catalysis, chemical sensing, and separation science. It is essential for researchers and manufacturers in pharmaceuticals, analytical chemistry, and materials science who require high-purity, functional macrocycles for advanced synthesis and complexation studies.

Application

• Phase-Transfer Catalyst: Facilitates reactions between reagents in immiscible phases, particularly useful in organic synthesis and industrial chemical manufacturing.
• Ion-Selective Electrodes & Sensors: Serves as an ionophore in the membrane of potentiometric sensors for detecting potassium (K⁺) and ammonium (NH₄⁺) ions.
• Metal Ion Extraction & Separation: Used in liquid-liquid extraction processes to selectively separate and recover specific alkali metal cations from complex mixtures.
• Pharmaceutical Intermediate: Acts as a building block in the synthesis of more complex crown ether derivatives with targeted biological activity.
• Research & Development: A key reagent in academic and industrial R&D for studying host-guest chemistry, supramolecular assembly, and molecular recognition.
• Analytical Chemistry: Employed as a chiral selector or complexing agent in chromatographic methods like HPLC for the separation of enantiomers or ionic species.

Basic Information

Product Name	4'-Aminobenzo-18-Crown-6
CAS No.	68941-06-0
Molecular Formula	C₁₆H₂₅NO₆
Molecular Weight	327.37 g/mol
Synonyms	4'-Amino-benzo-18-crown-6; 4-Aminobenzo-18-crown-6; Benzo-18-crown-6-4'-amine; 1-Aza-4,7,10,13,16-pentaoxacyclooctadeca-1,17-diene; 4-Aminodibenzo-18-crown-6 (common misnomer); 4'-NH₂-B18C6; Amino-functionalized B18C6; 4'-Amino-B18C6
EINECS	Contact for details

Quality Control

Our 4'-Aminobenzo-18-Crown-6 is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.