Description

2-(5-Bromopent-3-Ynyloxy)Tetrahydro-2H-Pyran is a specialized bromoalkyne derivative protected by a tetrahydropyranyl (THP) ether group. This compound is a high-value chemical building block prized for its dual functionality, enabling precise synthetic transformations in advanced organic chemistry. It is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery and development, particularly for candidates targeting neurological disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the alkyne and bromo groups allow for selective coupling reactions.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in cross-coupling reactions.
• Material Science Research: Employed in the synthesis of novel polymers and functional organic materials with tailored electronic or structural properties.
• Click Chemistry: The terminal alkyne moiety makes it a valuable substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, a cornerstone of bioconjugation and polymer science.
• Academic & R&D Laboratories: A versatile reagent for methodological studies in synthetic organic chemistry and the exploration of new reaction pathways.

Basic Information

Item	Details
Product Name	2-(5-Bromopent-3-Ynyloxy)Tetrahydro-2H-Pyran
CAS No.	68931-45-3
Molecular Formula	C10H15BrO2
Molecular Weight	247.13 g/mol
Synonyms	5-Bromo-3-pentynyl tetrahydropyranyl ether; 2H-Pyran, 2-[(5-bromo-3-pentynyl)oxy]tetrahydro-; THP ether of 5-bromopent-3-yn-1-ol; 5-Bromopent-3-yn-1-yl tetrahydropyran-2-yl ether; 3-Pentyn-1-ol, 5-bromo-, 1-(tetrahydro-2H-pyran-2-yl) ether; Bromoalkyne THP ether; Bromopentynyl THP ether
EINECS	Contact for details

Quality Control

Our production of 2-(5-Bromopent-3-Ynyloxy)Tetrahydro-2H-Pyran adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Every lot is characterized using advanced analytical techniques including GC, HPLC, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.