Description

(1R)-1,4Aα,5,6,7,7Aα-Hexahydro-6α-Hydroxy-1α-Methoxy-7α-Methylcyclopenta[C]Pyran-4-Carboxylic Acid Methyl Ester is a high-purity, synthetically derived chiral intermediate of significant importance in advanced organic synthesis. Its complex, functionalized cyclopentapyran structure makes it a valuable building block for the development of novel pharmaceutical compounds and fine chemicals. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific stereochemistry and molecular complexity into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological or inflammatory pathways.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where its specific stereochemistry can influence biological activity.
• Fine Chemical Production: Serves as a sophisticated precursor in the synthesis of complex fragrance molecules, dyes, and other high-value specialty chemicals.
• Academic & Industrial R&D: A valuable compound for methodological studies in asymmetric synthesis, catalysis, and natural product total synthesis.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	(1R)-1,4Aα,5,6,7,7Aα-Hexahydro-6α-Hydroxy-1α-Methoxy-7α-Methylcyclopenta[C]Pyran-4-Carboxylic Acid Methyl Ester
CAS No.	68736-83-4
Molecular Formula	C12H18O5
Molecular Weight	242.27 g/mol
Synonyms	Methyl (1R,1aR,4aS,7aR)-1-methoxy-7a-methyl-1,1a,4,4a,5,6,7,7a-octahydrocyclopropa[e]isochromene-4-carboxylate; (1R,1aR,4aS,7aR)-1-Methoxy-7a-methyl-1,1a,4,4a,5,6,7,7a-octahydrocyclopropa[e]isochromene-4-carboxylic acid methyl ester; 1-Methoxy-7a-methyl-1,1a,4,4a,5,6,7,7a-octahydrocyclopropa[e]isochromene-4-carboxylic acid methyl ester; A key chiral intermediate of the cyclopentapyran class.
EINECS	Contact for details

Quality Control

Our (1R)-1,4Aα,5,6,7,7Aα-Hexahydro-6α-Hydroxy-1α-Methoxy-7α-Methylcyclopenta[C]Pyran-4-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.