Description

4H-Pyran-4-One, 2,3-Dihydro-5-Hydroxy-2-(Hydroxymethyl)-, (2S)- is a high-purity chiral intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a versatile building block in the production of complex, biologically active molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including potential antiviral or anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the creation of advanced, targeted pesticides and herbicides where specific stereochemistry is crucial for activity.
• Fine Chemical Production: Serves as a foundational block for synthesizing complex flavors, fragrances, and functional materials.
• Academic & Research: Employed in organic chemistry research for methodological studies in asymmetric synthesis and heterocyclic chemistry.
• Bioconjugate Chemistry: Potential use in modifying biomolecules or creating drug-linker systems due to its functional groups.
• Catalyst Ligand Precursor: Can be utilized to develop novel chiral ligands for asymmetric catalysis.

Basic Information

Product Name	4H-Pyran-4-One, 2,3-Dihydro-5-Hydroxy-2-(Hydroxymethyl)-, (2S)-
CAS No.	68732-99-0
Molecular Formula	C6H8O4
Molecular Weight	144.13 g/mol
Synonyms	(2S)-2,3-Dihydro-5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one; (S)-2-(Hydroxymethyl)-2,3-dihydro-5-hydroxy-4H-pyran-4-one; L-(-)-Kojic acid derivative; (2S)-5-Hydroxy-2-(hydroxymethyl)-2,3-dihydro-4H-pyran-4-one; Chiral dihydropyranone; (S)-Dihydro-5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one
EINECS	Contact for details

Quality Control

Our 4H-Pyran-4-One, 2,3-Dihydro-5-Hydroxy-2-(Hydroxymethyl)-, (2S)- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and synthesis applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.