Description

n-Boc-m-Phenylenediamine is a protected aromatic diamine derivative of significant importance in synthetic organic chemistry. This compound serves as a versatile and critical building block, enabling the controlled introduction of an aniline moiety into complex molecular architectures. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of active pharmaceutical ingredients (APIs), ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where its aromatic amine functionality is essential.
• Polymer Chemistry: Serves as a monomer or chain extender in the synthesis of high-performance polyamides, polyimides, and polyurea resins.
• Ligand and Catalyst Development: Employed in the preparation of nitrogen-containing ligands for metal complexes used in catalysis.
• Dye and Pigment Manufacturing: Acts as a precursor in the synthesis of azo dyes and other complex organic colorants.
• Peptide Mimetics and Bioconjugation: The Boc-protected amine allows for selective reactions in the synthesis of peptide analogs and bioconjugation linkers.
• Research and Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	n-Boc-m-Phenylenediamine
CAS No.	68621-88-5
Molecular Formula	C11H16N2O2
Molecular Weight	208.26 g/mol
Synonyms	1,3-Phenylenediamine, N-Boc-protected; 3-((tert-Butoxycarbonyl)amino)aniline; 1-Amino-3-((tert-butoxycarbonyl)amino)benzene; tert-Butyl (3-aminophenyl)carbamate; N-(3-Aminophenyl)carbamic acid tert-butyl ester; m-Phenylenediamine, N-Boc derivative; Boc-m-PDA; Boc-1,3-diaminobenzene
EINECS	Contact for details

Quality Control

Our n-Boc-m-Phenylenediamine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided and available upon request. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	108 - 112 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.