Description

4-Pentyn-1-Ol, 1-Methanesulfonate is a specialized organic building block featuring both a terminal alkyne and a mesylate leaving group, making it a versatile intermediate for advanced synthesis. This compound is critical for researchers and manufacturers developing pharmaceuticals, agrochemicals, and novel materials through cross-coupling and nucleophilic substitution reactions. It is particularly valuable for medicinal chemistry applications, including the synthesis of targeted small molecule inhibitors and bioconjugates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and prodrugs, especially those requiring alkyne functionalization for click chemistry.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Bioconjugation & Probe Development: The terminal alkyne group is essential for creating fluorescent probes, biomarkers, and antibody-drug conjugates (ADCs) via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D for constructing complex molecular architectures through Sonogashira and other palladium-catalyzed couplings.
• Liquid Crystal & Electronic Chemical Production: Used in the synthesis of organic semiconductors and liquid crystal compounds for display technologies.

Basic Information

Product Name	4-Pentyn-1-Ol, 1-Methanesulfonate
CAS No.	68275-03-6
Molecular Formula	C6H10O4S
Molecular Weight	178.21 g/mol
Synonyms	1-Methanesulfonyloxy-4-pentyne; 4-Pentyn-1-yl methanesulfonate; Pent-4-yn-1-yl methanesulfonate; 4-Pentyne-1-ol methanesulfonate; 4-Pentynyl methanesulfonate; 1-Hydroxy-4-pentyne methanesulfonate; Mesylate ester of 4-pentyn-1-ol
EINECS	Contact for details

Quality Control

Our 4-Pentyn-1-Ol, 1-Methanesulfonate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider using an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.