Description

3-Amino-3-(4-Methylphenyl)Propionic Acid is a specialized aromatic amino acid derivative that serves as a versatile chiral building block in advanced organic synthesis. Its molecular structure, featuring both an amino and a carboxylic acid functional group on a propionic acid backbone attached to a methylphenyl ring, makes it a critical intermediate for constructing complex molecules with high stereochemical purity. This compound is essential for research and development chemists and process engineers in the pharmaceutical and fine chemical industries who require high-purity, reliable intermediates for API synthesis and the development of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and metabolic disorders.
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and mimetics to improve metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural products, agrochemicals, and specialty chemicals.
• Bioconjugation and Linker Chemistry: The carboxylic acid and amino groups facilitate its use as a bifunctional linker in bioconjugation techniques for antibody-drug conjugates (ADCs) or diagnostic probes.
• Academic and R&D Laboratories: A valuable compound for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	3-Amino-3-(4-Methylphenyl)Propionic Acid
CAS No.	68208-18-4
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	3-Amino-3-(p-tolyl)propanoic acid; β-Amino-4-methylhydrocinnamic acid; (3-Amino-3-(4-methylphenyl)propanoic acid; 3-Amino-3-(4-methylphenyl)propanoic acid; 4-Methyl-β-phenyl-β-alanine; DL-3-Amino-3-(4-methylphenyl)propionic acid; 68208-18-4; (RS)-3-Amino-3-(4-methylphenyl)propionic acid
EINECS	Contact for details

Quality Control

Our 3-Amino-3-(4-Methylphenyl)Propionic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the exacting standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.