Description

2-Bromo-3-Nitroanisole is a versatile halogenated aromatic ether, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of its bromo and nitro substituents, which enable selective functionalization for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring a substituted anisole core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its reactive halogen site.
• Dye and Pigment Manufacturing: Serves as a precursor for synthesizing specialized azo dyes and other colorants due to its nitro and methoxy groups.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers as a functional monomer.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, or Buchwald-Hartwig amination for carbon-carbon and carbon-heteroatom bond formation.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic synthesis and for creating compound libraries for screening.

Basic Information

Product Name	2-Bromo-3-Nitroanisole
CAS No.	67853-37-6
Molecular Formula	C7H6BrNO3
Molecular Weight	232.03 g/mol
Synonyms	1-Bromo-2-methoxy-3-nitrobenzene; 3-Nitro-2-bromoanisole; Benzene, 1-bromo-2-methoxy-3-nitro-; 2-Methoxy-6-nitrobenzyl bromide (incorrect but common alias); o-Bromo-m-nitroanisole
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for 2-Bromo-3-Nitroanisole to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with comprehensive identity confirmation via FT-IR and NMR. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics. Custom purity grades and analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque to prevent photochemical degradation.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.