Description

(4Ar)-4Aα,5,6,7,7Aβ,8,8Aβ,8Bα-Octahydro-1,8,8-Trimethyl-5-Methylene-4H-Cyclopropa[3,4]Cyclohepta[1,2-C]Pyran-4-One CAS NO 67779-72-0 is a complex sesquiterpene lactone derivative, a class of compounds known for their significant biological activity and structural complexity. This specialized chemical serves as a high-value intermediate in advanced organic synthesis, particularly for the development of novel pharmacologically active molecules. It is primarily sought after by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of terpenoid-based compounds, natural product analogs, and new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting anti-inflammatory or anti-cancer pathways.
• Natural Product Synthesis: Used in the total or semi-synthesis of complex sesquiterpenes and related natural products for research and development.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to explore new bioactive molecules.
• Fine Chemical Production: Intermediate in the manufacture of high-purity, specialty chemicals for advanced material science applications.
• Reference Standard: Used as an analytical standard in quality control laboratories for the identification and quantification of related compounds.
• Fragrance & Flavor Precursor: Potential intermediate for synthesizing unique terpenoid-based aroma chemicals, given its structural backbone.

Basic Information

Product Name	(4Ar)-4Aα,5,6,7,7Aβ,8,8Aβ,8Bα-Octahydro-1,8,8-Trimethyl-5-Methylene-4H-Cyclopropa[3,4]Cyclohepta[1,2-C]Pyran-4-One
CAS No.	67779-72-0
Molecular Formula	C15H20O2
Molecular Weight	232.32 g/mol
Synonyms	4H-Cyclopropa[3,4]cyclohepta[1,2-c]pyran-4-one, octahydro-1,8,8-trimethyl-5-methylene-, [4aR-(4aα,5β,7aβ,8aβ,8bα)]-; 1,8,8-Trimethyl-5-methylene-4a,5,6,7,7a,8,8a,8b-octahydro-4H-cyclopropa[3,4]cyclohepta[1,2-c]pyran-4-one; A sesquiterpene lactone derivative. Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our production of (4Ar)-4Aα,5,6,7,7Aβ,8,8Aβ,8Bα-Octahydro-1,8,8-Trimethyl-5-Methylene-4H-Cyclopropa[3,4]Cyclohepta[1,2-C]Pyran-4-One adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity, critical for research and synthesis applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment. While typically supplied as a research-grade chemical, production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation and light, prolonged exposure to air or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.