Description

(S)-(+)-2-Hydroxymethyl-3,4-Dihydro-2H-Pyran is a chiral, non-racemic heterocyclic building block of significant synthetic utility. This compound matters as a versatile intermediate for the stereoselective synthesis of complex molecules, particularly in the pharmaceutical and fine chemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), natural product analogs, and advanced chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of biologically active compounds, including potential antiviral, antibacterial, and anticancer agents.
• Asymmetric Synthesis: Used in the construction of complex, enantiomerically pure natural products and their derivatives.
• Catalyst & Ligand Development: Serves as a precursor for novel chiral ligands and organocatalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Industrial Research: A valuable tool for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	(S)-(+)-2-Hydroxymethyl-3,4-Dihydro-2H-Pyran
CAS No.	67666-30-2
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	(S)-(+)-2-(Hydroxymethyl)-3,4-dihydro-2H-pyran; (S)-2-Hydroxymethyl-3,4-dihydro-2H-pyran; (S)-2-(Hydroxymethyl)-3,4-dihydro-2H-pyran; (S)-Tetrahydro-2H-pyran-2-methanol; (S)-3,4-Dihydro-2H-pyran-2-methanol; (S)-DHP-methanol; (S)-Glycidol dihydropyranyl ether (precursor form)
EINECS	Contact for details

Quality Control

Our (S)-(+)-2-Hydroxymethyl-3,4-Dihydro-2H-Pyran is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure compliance with exacting customer specifications and industry standards. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is light-sensitive and easily oxidized; allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.