Description

5-Fluoro-2-Methoxy-Benzenesulfonyl Chloride is a versatile and high-purity sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its reactivity as a sulfonylation reagent, enabling the introduction of the sulfonyl functional group into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of new herbicides and fungicides that require the sulfonyl moiety for biological activity.
• Chemical Research & Development: A valuable reagent in medicinal chemistry for creating compound libraries and exploring structure-activity relationships (SAR).
• Dye and Pigment Manufacturing: Employed in the synthesis of specialty dyes and functional materials.
• Polymer Chemistry: Can be used to modify polymers or create monomers with specific sulfonyl group properties.

Basic Information

Product Name	5-Fluoro-2-Methoxy-Benzenesulfonyl Chloride
CAS No.	67457-56-3
Molecular Formula	C7H6ClFO3S
Molecular Weight	224.64 g/mol
Synonyms	2-Methoxy-5-fluorobenzenesulfonyl chloride; 5-Fluoro-2-methoxybenzenesulfonyl chloride; 5-Fluoro-o-anisylsulfonyl chloride; 2-Methoxy-5-fluorophenylsulfonyl chloride; 67457-56-3; 5-Fluoro-2-methoxybenzene-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Methoxy-Benzenesulfonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.