Description

1-[(5H-Dibenzo[A,D]Cyclohepten-5-Yl)Sulfonyl]-4-Phenyl-4-Piperidinecarboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate of significant importance in modern organic synthesis. This compound is valued for its complex molecular architecture, which serves as a critical building block in the development of active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel therapeutic agents, particularly within central nervous system (CNS) and receptor-targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Process Development: Serves as a critical raw material for scaling up synthetic routes from laboratory to pilot and commercial production.
• Reference Standard: Employed as an analytical standard for quality control, method development, and regulatory submissions.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	1-[(5H-Dibenzo[A,D]Cyclohepten-5-Yl)Sulfonyl]-4-Phenyl-4-Piperidinecarboxylic Acid Ethyl Ester
CAS No.	67361-14-2
Molecular Formula	C29H27NO4S
Molecular Weight	485.59 g/mol
Synonyms	Ethyl 1-[(5H-dibenzo[a,d]cyclohepten-5-yl)sulfonyl]-4-phenyl-4-piperidinecarboxylate; 4-Phenyl-1-[(5H-dibenzo[a,d]cyclohepten-5-yl)sulfonyl]-4-piperidinecarboxylic acid ethyl ester; 1-(5H-Dibenzo[a,d]cyclohepten-5-ylsulfonyl)-4-phenylpiperidine-4-carboxylic acid ethyl ester; NSC 339539; 67361-14-2; Ethyl 4-phenyl-1-(5H-dibenzo[a,d]cyclohepten-5-ylsulfonyl)piperidine-4-carboxylate
EINECS	Contact for details

Quality Control

Our production of this pharmaceutical intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical specifications. We support our partners in meeting the stringent requirements for GMP-grade intermediates and regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.