Description

(2S)-1-(3-Nitrophenyl)Sulfonylproline CAS NO 67320-37-0 is a high-purity chiral proline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with defined stereochemistry, essential for research and development in regulated industries. This compound is primarily needed by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in protease inhibitor and other targeted therapeutic areas.
• Agrochemical Synthesis: Used in the design and production of advanced, enantiomerically pure crop protection agents and herbicides.
• Peptidomimetics & Drug Discovery: A fundamental component in medicinal chemistry for creating peptide analogs and probing structure-activity relationships (SAR).
• Catalyst & Ligand Development: Serves as a precursor for synthesizing specialized chiral catalysts and ligands used in asymmetric synthesis.
• Bioconjugation & Chemical Biology: Useful in developing probes and linkers for studying biological systems and creating antibody-drug conjugates (ADCs).
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and material science laboratories.

Basic Information

Product Name	(2S)-1-(3-Nitrophenyl)Sulfonylproline
CAS No.	67320-37-0
Molecular Formula	C11H12N2O6S
Molecular Weight	300.29 g/mol
Synonyms	L-Proline, 1-[(3-nitrophenyl)sulfonyl]-; (S)-1-(3-Nitrobenzenesulfonyl)pyrrolidine-2-carboxylic acid; 1-(3-Nitrobenzenesulfonyl)-L-proline; (2S)-1-[(3-Nitrophenyl)sulfonyl]pyrrolidine-2-carboxylic acid; 3-Nitrobenzenesulfonyl-L-proline; N-(3-Nitrobenzenesulfonyl)-L-proline; (S)-1-(3-Nitrophenylsulfonyl)proline; NSC 339586
EINECS	Contact for details

Quality Control

Our (2S)-1-(3-Nitrophenyl)Sulfonylproline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.