Description

4-[(2-o-Methyl-6-Deoxy-L-Mannopyranosyl)Oxy]-3,4-Dihydro-3,9-Dimethoxy-2-Methyl-2,5,7-Trihydroxy-1,6,11(2H)-Naphthacenetrione is a complex, high-purity chemical intermediate with significant value in advanced organic synthesis. Its intricate molecular architecture, featuring a naphthacenetrione core linked to a modified sugar moiety, makes it a critical building block for research and development in specialized pharmaceutical applications. This compound is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly in the fields of oncology and antibiotics.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel anthracycline and tetracycline analogue drug candidates.
• Anticancer Agent Research: Used in medicinal chemistry programs to develop and evaluate new chemotherapeutic compounds targeting DNA intercalation.
• Antibiotic Development: Acts as a sophisticated scaffold for creating next-generation antibiotics with modified mechanisms of action.
• Biochemical Research: Employed in studies investigating the interaction of complex polyketide-derived molecules with biological targets.
• Process Chemistry: Utilized in route scouting and optimization for the commercial-scale production of high-value active pharmaceutical ingredients (APIs).
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	4-[(2-o-Methyl-6-Deoxy-L-Mannopyranosyl)Oxy]-3,4-Dihydro-3,9-Dimethoxy-2-Methyl-2,5,7-Trihydroxy-1,6,11(2H)-Naphthacenetrione
CAS No.	67314-27-6
Molecular Formula	C27H30O13
Molecular Weight	562.52 g/mol
Synonyms	4-[(2-O-Methyl-6-deoxy-α-L-mannopyranosyl)oxy]-3,4-dihydro-3,9-dimethoxy-2-methyl-2,5,7-trihydroxy-1,6,11(2H)-naphthacenetrione; 2-O-Methyl-6-deoxy-α-L-mannopyranosyl derivative of aklavinone; Aklavinone 2'-O-methyl-α-L-rhamnoside; Related to Aclacinomycin A aglycone; Modified Anthracycline Glycoside; 67314-27-6; 4-[(2-O-Methyl-6-deoxy-L-mannopyranosyl)oxy]-3,4-dihydro-3,9-dimethoxy-2-methyl-2,5,7-trihydroxy-1,6,11(2H)-naphthacenetrione
EINECS	Contact for details

Quality Control

Every batch of 4-[(2-o-Methyl-6-Deoxy-L-Mannopyranosyl)Oxy]-3,4-Dihydro-3,9-Dimethoxy-2-Methyl-2,5,7-Trihydroxy-1,6,11(2H)-Naphthacenetrione is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request, supporting compliance with cGMP and research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Orange to red-brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.