Description

4-[(2-o-Methyl-6-Deoxy-D-Mannopyranosyl)Oxy]-3,4-Dihydro-3,9-Dimethoxy-2-Methyl-2,5,7-Trihydroxy-1,6,11(2H)-Naphthacenetrione CAS NO 67314-26-5 is a complex, high-purity anthracycline glycoside derivative. This compound is valued for its role as a critical pharmaceutical intermediate and a key structural motif in advanced research. It is primarily required by pharmaceutical R&D and fine chemical synthesis sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel anthracycline-based chemotherapeutic agents and antibiotics.
• Biochemical Research: Used as a reference standard and probe in studies of DNA intercalation, topoisomerase inhibition, and anticancer mechanisms.
• Academic & Discovery Chemistry: Serves as a sophisticated starting material for medicinal chemistry programs targeting cancer and microbial infections.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex natural product analogs and specialty molecules.
• Reference Material: Provides a high-purity standard for analytical method development, quality control, and regulatory submissions in the pharma industry.

Basic Information

Item	Details
Product Name	4-[(2-o-Methyl-6-Deoxy-D-Mannopyranosyl)Oxy]-3,4-Dihydro-3,9-Dimethoxy-2-Methyl-2,5,7-Trihydroxy-1,6,11(2H)-Naphthacenetrione
CAS No.	67314-26-5
Molecular Formula	C28H30O13
Molecular Weight	574.53 g/mol
Synonyms	4-[(2-O-Methyl-6-deoxy-α-L-mannopyranosyl)oxy]-3,4-dihydro-3,9-dimethoxy-2-methyl-2,5,7-trihydroxy-1,6,11(2H)-naphthacenetrione; 2-O-Methyl-6-deoxy-α-L-mannopyranosyl derivative of aklavinone; Aklavinone 2'-O-methyl-α-L-rhamnoside; Related to Aclacinomycin/ Aclarubicin intermediates; Anthracycline glycoside derivative; 67314-26-5; (2'R)-2'-O-Methylaklavinone α-L-rhamnoside
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure structural identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with each shipment to support your R&D and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a dry, cool place. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Orange to red-brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.