Description

2-Bromo-4-Methoxybenzyl Chloride (+ Regioisomers) is a versatile and high-value halogenated benzyl chloride derivative used as a critical building block in advanced organic synthesis. Its structure makes it an essential intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought after by research institutions and industrial manufacturers developing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the bromo and chloro substituents enable further functionalization.
• Liquid Crystal Materials: Serves as a building block for mesogenic compounds used in display technologies.
• Organic Light-Emitting Diodes (OLEDs): Intermediate in the manufacture of electron-transport or host materials for OLED devices.
• Cross-Coupling Reactions: Valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating specialized chemical libraries.

Basic Information

Product Name	2-Bromo-4-Methoxybenzyl Chloride (+ Regioisomers)
CAS No.	66916-97-0
Molecular Formula	C8H8BrClO
Molecular Weight	235.51 g/mol
Synonyms	1-(Bromomethyl)-2-methoxy-4-chlorobenzene; 2-Bromo-4-methoxybenzyl chloride; 4-Methoxy-2-bromobenzyl chloride; (2-Bromo-4-methoxyphenyl)methyl chloride; α-Chloro-2-bromo-4-methoxytoluene; Benzene, 1-(bromomethyl)-2-methoxy-4-chloro-; 2-Bromo-4-methoxybenzyl chloride (contains regioisomers)
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Methoxybenzyl Chloride (+ Regioisomers) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profile is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Total of isomers)
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Report and comply with customer requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.