Description

(2R,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanoic Acid Hydrate is a high-purity, stereochemically defined derivative of gluconic acid, commonly known as D-Gluconic Acid. This compound is valued for its role as a versatile chiral building block and chelating agent in advanced chemical synthesis. It is essential for manufacturers in the pharmaceutical, food, and personal care industries seeking a high-quality, water-soluble organic acid with specific stereochemistry for critical applications.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting metabolic pathways.
• Food Additive & Chelating Agent: Used as a sequestrant and acidity regulator in food and beverage processing to stabilize color and flavor.
• Cosmetics & Personal Care: Incorporated into formulations for its mild chelating, moisturizing, and pH-adjusting properties in skin and hair care products.
• Industrial Cleaning & Derusting: Acts as an effective, biodegradable component in industrial cleaning solutions and metal surface treatment processes.
• Chemical Synthesis: Employed as a starting material or ligand in asymmetric synthesis and catalysis due to its multiple hydroxyl groups.
• Nutrient & Supplement Precursor: Used in the production of mineral gluconates (e.g., calcium, zinc gluconate) for nutritional supplements.

Basic Information

Product Name	(2R,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanoic Acid Hydrate
CAS No.	66905-24-6
Molecular Formula	C6H12O7 • xH2O
Molecular Weight	196.16 (Anhydrous basis)
Synonyms	D-Gluconic Acid Hydrate; (2R,3S,4R,5R)-2,3,4,5,6-Pentahydroxycaproic Acid Hydrate; Gluconic Acid (D-); Dextronic Acid; Maltonic Acid; 2,3,4,5,6-Pentahydroxyhexanoic Acid; D-Gluconate; CAS 526-95-4 (anhydrous form)
EINECS	208-401-4 (for D-Gluconic Acid)

Quality Control

Our (2R,3S,4R,5R)-2,3,4,5,6-Pentahydroxyhexanoic Acid Hydrate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure compliance with relevant industry standards, including specifications for pharmaceutical (USP/EP) or food grade (FCC) applications where applicable. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers must be kept tightly sealed after opening to minimize exposure to air and moisture. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Specific Rotation [α]20/D	-5.0° to -7.0° (c=1 in H2O)
Water Content (KF)	As per hydrate specification (e.g., 5-15%)
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%
pH (5% solution)	3.0 - 4.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.