Description

5,5,5-Trifluoropentanoic Acid Methyl Ester is a high-purity fluorinated building block essential for advanced organic synthesis. This compound matters for its unique trifluoromethyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting metabolic diseases and CNS disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving performance and stability.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, enhancing their chemical resistance and surface properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, esterifications, and nucleophilic substitutions to construct complex fluorinated molecules.
• Proteomics & Biochemistry Research: Acts as a reagent for labeling or modifying biomolecules in research applications.

Basic Information

Product Name	5,5,5-Trifluoropentanoic Acid Methyl Ester
CAS No.	66716-19-6
Molecular Formula	C6H9F3O2
Molecular Weight	170.13 g/mol
Synonyms	Methyl 5,5,5-Trifluoropentanoate; Methyl 5,5,5-Trifluorovalerate; 5,5,5-Trifluorovaleric Acid Methyl Ester; Pentanoic Acid, 5,5,5-Trifluoro-, Methyl Ester; 66716-19-6; Methyl 4,4,4-Trifluorobutylcarboxylate; Trifluoropentanoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 5,5,5-Trifluoropentanoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place away from strong bases and incompatible materials. Due to its highly volatile nature, keep containers tightly sealed and handle in a fume hood. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.