Description

Pyridazine, 3-Chloro-6-[4-(Trifluoromethyl)Phenyl]- is a high-value, halogenated heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring a pyridazine core substituted with chloro and trifluoromethylphenyl groups, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Pyridazine, 3-Chloro-6-[4-(Trifluoromethyl)Phenyl]-
CAS No.	66548-88-7
Molecular Formula	C11H6ClF3N2
Molecular Weight	258.62 g/mol
Synonyms	3-Chloro-6-[4-(trifluoromethyl)phenyl]pyridazine; 3-Chloro-6-(4-trifluoromethylphenyl)pyridazine; 6-(4-Trifluoromethylphenyl)-3-chloropyridazine; 3-Chloro-6-(alpha,alpha,α-trifluoro-p-tolyl)pyridazine; 4-(3-Chloropyridazin-6-yl)benzotrifluoride; 3-Chloro-6-(4-trifluoromethyl-phenyl)-pyridazine; 3-Chloro-6-(p-trifluoromethylphenyl)pyridazine
EINECS	Contact for details

Quality Control

Our Pyridazine, 3-Chloro-6-[4-(Trifluoromethyl)Phenyl]- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.