Description

[1R,4S,(+)]-2-[(1E,2E)-2-Butene-1-Ylidene]-1,3,3-Trimethyl-7-Oxabicyclo[2.2.1]Heptane CAS NO 66495-46-3 is a high-purity, optically active bicyclic ether compound characterized by its specific stereochemistry and conjugated diene system. This compound matters as a valuable chiral building block and intermediate in advanced organic synthesis, offering a rigid molecular framework for constructing complex target molecules. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty fragrance industries for applications in asymmetric synthesis and material science.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in stereoselective synthesis.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and pesticides where specific stereochemistry is crucial for biological activity.
• Fine Chemical Synthesis: Acts as a precursor for complex natural product analogs and specialty chemicals requiring its unique bicyclic structure.
• Material Science: Investigated as a monomer or cross-linking agent for creating polymers with specific optical or structural properties.
• Asymmetric Catalysis: Employed as a ligand precursor or a substrate in catalytic reactions to study and induce chirality.
• Fragrance & Flavor Chemistry: Utilized in the research and development of novel aroma chemicals due to its complex, oxygenated terpene-like backbone.

Basic Information

Product Name	[1R,4S,(+)]-2-[(1E,2E)-2-Butene-1-Ylidene]-1,3,3-Trimethyl-7-Oxabicyclo[2.2.1]Heptane
CAS No.	66495-46-3
Molecular Formula	C13H20O
Molecular Weight	192.30 g/mol
Synonyms	(+)-2-[(1E,2E)-2-Buten-1-ylidene]-1,3,3-trimethyl-7-oxabicyclo[2.2.1]heptane; (1R,4S)-2-[(1E,2E)-2-Buten-1-ylidene]-1,3,3-trimethyl-7-oxabicyclo[2.2.1]heptane; (1R,4S)-(+)-2-[(1E,2E)-2-Butenylidene]-1,3,3-trimethyl-7-oxabicyclo[2.2.1]heptane; 7-Oxabicyclo[2.2.1]heptane, 2-[(1E,2E)-2-buten-1-ylidene]-1,3,3-trimethyl-, (1R,4S)-; (+)-Oxabicycloheptane derivative; Chiral oxabicyclic diene
EINECS	Contact for details

Quality Control

Our [1R,4S,(+)]-2-[(1E,2E)-2-Butene-1-Ylidene]-1,3,3-Trimethyl-7-Oxabicyclo[2.2.1]Heptane is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.