Description

Cyclobutane, 2-Ethynyl-1,1,3,3-Tetramethyl- (9Ci) is a specialized organic building block featuring a strained cyclobutane ring and a reactive ethynyl (acetylene) functional group. This unique molecular architecture makes it a valuable intermediate for advanced organic synthesis and materials science research. It is primarily sought after by R&D chemists and process developers in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for creating constrained ring systems.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Specialty Polymer Monomer: Acts as a precursor for high-performance polymers, including those with tailored optical or mechanical properties.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: Utilized in the creation of advanced organic electronic materials and molecular scaffolds.
• Cross-Coupling Reactions: The ethynyl group is pivotal in Sonogashira and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	Cyclobutane, 2-Ethynyl-1,1,3,3-Tetramethyl- (9Ci)
CAS No.	66438-89-9
Molecular Formula	C10H16
Molecular Weight	136.23 g/mol
Synonyms	2-Ethynyl-1,1,3,3-tetramethylcyclobutane; 1,1,3,3-Tetramethyl-2-ethynylcyclobutane; Tetramethyl(ethynyl)cyclobutane; 2-Ethynyltetramethylcyclobutane
EINECS	Contact for details

Quality Control

Our Cyclobutane, 2-Ethynyl-1,1,3,3-Tetramethyl- (9Ci) is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat, sparks, and open flames. Due to its highly volatile nature, keep the container tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.