Description

3-Trimethylsilyl-3-buten-2-ol is a versatile organosilicon compound featuring both a silyl-protected alcohol and an alkene functional group, making it a valuable building block in synthetic organic chemistry. Its primary value lies in its dual reactivity, serving as a protected synthon for carbonyl compounds and a precursor for silyl enol ethers, which are crucial intermediates in various carbon-carbon bond-forming reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, specialized intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules, particularly in routes requiring silyl-protected intermediates or specific stereochemistry.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its functional groups enable the construction of specific active molecular frameworks.
• Organometallic Chemistry: Acts as a ligand precursor or a substrate in reactions involving transition metal catalysts for cross-coupling and other catalytic transformations.
• Polymer & Material Science: Serves as a monomer or functionalization agent for creating silicon-containing polymers with tailored properties like thermal stability or specific surface characteristics.
• Fine Chemical Production: Employed in the multistep synthesis of flavors, fragrances, and other high-value specialty chemicals.
• Academic & R&D: A valuable reagent for methodological development in organic synthesis, exploring new reaction pathways involving silyl enol ethers.

Basic Information

Product Name	3-Trimethylsilyl-3-buten-2-ol
CAS No.	66374-47-8
Molecular Formula	C7H16OSi
Molecular Weight	144.29 g/mol
Synonyms	3-Buten-2-ol, 3-(trimethylsilyl)-; 3-(Trimethylsilyl)-3-buten-2-ol; 3-Trimethylsilylbut-3-en-2-ol; TMS-Protected Butenol; 1-Trimethylsilyl-1-buten-3-ol; (3-Trimethylsilyl-3-buten-2-yl) alcohol
EINECS	Contact for details

Quality Control

Our 3-Trimethylsilyl-3-buten-2-ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and HPLC, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.