Description

2-Amino-6-Chloro-1,2,3,4-Tetrahydro-Naphthalen-1-Ol Hydrochloride is a high-purity, pharmaceutically relevant organic intermediate characterized by its tetralin-based structure. This compound matters as a critical building block in the synthesis of complex molecules, offering a chiral scaffold for developing active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of central nervous system (CNS) and cardiovascular drug candidates.
• Organic Synthesis Building Block: Used in the construction of complex tetralin and naphthalene derivatives for medicinal chemistry programs.
• Chemical Research: Serves as a standard or starting material in academic and industrial laboratories studying stereoselective synthesis.
• Process Chemistry: Employed in scale-up and optimization studies for the production of advanced pharmaceutical intermediates.

Basic Information

Product Name	2-Amino-6-Chloro-1,2,3,4-Tetrahydro-Naphthalen-1-Ol Hydrochloride
CAS No.	66361-36-2
Molecular Formula	C₁₀H₁₃Cl₂NO
Molecular Weight	234.12 g/mol
Synonyms	6-Chloro-1,2,3,4-tetrahydro-1-hydroxy-2-naphthylamine hydrochloride; 2-Amino-6-chloro-1-tetralol hydrochloride; 1-Amino-6-chloro-2-hydroxy-1,2,3,4-tetrahydronaphthalene hydrochloride; (1R,2S)-rel-2-Amino-6-chloro-1,2,3,4-tetrahydro-1-naphthalenol hydrochloride (if racemic); 2-Amino-6-chloro-α-tetralol hydrochloride; 6-Chloro-2-amino-α-tetralol hydrochloride; 1-Hydroxy-2-amino-6-chlorotetralin hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-6-Chloro-1,2,3,4-Tetrahydro-Naphthalen-1-Ol Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.