Description

3-Chloro-6-Pyrrolidin-1-Yl-Pyridazine is a heterocyclic organic compound featuring a pyridazine core substituted with chlorine and a pyrrolidine group, serving as a versatile and high-value chemical building block. Its molecular architecture makes it a critical intermediate in advanced organic synthesis, particularly for constructing complex nitrogen-containing scaffolds. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Synthesis Building Block: Employed in organic chemistry for constructing complex polycyclic systems and functionalized heterocycles via cross-coupling and substitution reactions.
• Material Science Research: Investigated as a monomer or functional component in the creation of advanced polymers and organic electronic materials.
• Academic & R&D Laboratories: Serves as a standard reagent for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	3-Chloro-6-Pyrrolidin-1-Yl-Pyridazine
CAS No.	66346-85-8
Molecular Formula	C9H11ClN4
Molecular Weight	210.66 g/mol
Synonyms	3-Chloro-6-(1-pyrrolidinyl)pyridazine; 3-Chloro-6-pyrrolidin-1-ylpyridazine; 6-Pyrrolidin-1-yl-3-chloropyridazine; 3-Chloro-6-(pyrrolidin-1-yl)pyridazine; 66346-85-8; Pyrrolidine, 1-(6-chloro-3-pyridazinyl)-; 1-(6-Chloro-3-pyridazinyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our 3-Chloro-6-Pyrrolidin-1-Yl-Pyridazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH limits
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.