Description

(3S,5S)-2-Azidomethyl-6-Methoxy-Tetrahydro-Pyran-3,4,5-Triol is a high-purity, stereochemically defined carbohydrate derivative featuring an azido functional group. This compound is a critical chiral building block and intermediate in the synthesis of complex pharmaceuticals, particularly nucleoside analogs and antiviral agents. It is essential for research and development in medicinal chemistry, process chemistry, and fine chemical manufacturing, where precise stereochemistry and functional group compatibility are paramount. The CAS number for this compound is 66224-56-4.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel nucleoside analogs and antiviral drugs.
• Medicinal Chemistry Research: Used in the discovery and development of new therapeutic agents targeting viral infections.
• Process Chemistry: Serves as a building block in the scalable production of active pharmaceutical ingredients (APIs).
• Glycochemistry & Glycobiology: Employed in the synthesis of modified sugars and carbohydrate-based molecules for biological studies.
• Click Chemistry: The azido group enables efficient conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and material science applications.
• Fine Chemical Synthesis: A versatile intermediate for creating complex, stereochemically rich organic molecules.

Basic Information

Product Name	(3S,5S)-2-Azidomethyl-6-Methoxy-Tetrahydro-Pyran-3,4,5-Triol
CAS No.	66224-56-4
Molecular Formula	C8H15N3O5
Molecular Weight	233.22 g/mol
Synonyms	2-Azidomethyl-6-methoxy-tetrahydropyran-3,4,5-triol; (3S,5S)-2-(Azidomethyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol; 6-Methoxy-2-azidomethyl-tetrahydropyran-3,4,5-triol; Azidomethyl methoxy tetrahydropyran triol; Carbohydrate azide derivative
EINECS	Contact for details

Quality Control

Our (3S,5S)-2-Azidomethyl-6-Methoxy-Tetrahydro-Pyran-3,4,5-Triol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and stereochemical integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store the material under an inert atmosphere for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.