Description

2-Bromo-1-Bromomethyl-5-Chlorobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both bromomethyl and chloro substituents on a brominated benzene ring, makes it a critical precursor for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and as a key intermediate in active ingredient development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where its halogen atoms provide sites for further functionalization.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands for metal catalysis and organocatalysts.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags due to the reactivity of the bromomethyl group for bioconjugation.
• Cross-Coupling Reactions: A valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.

Basic Information

Item	Details
Product Name	2-Bromo-1-Bromomethyl-5-Chlorobenzene
CAS No.	66192-24-3
Molecular Formula	C7H5Br2Cl
Molecular Weight	284.38 g/mol
Synonyms	1,2-Dibromo-4-Chlorotoluene; 2-Bromo-α-bromo-4-chlorotoluene; 4-Chloro-α,2-dibromotoluene; 1-Bromomethyl-2-bromo-4-chlorobenzene; 4-Chloro-2-bromobenzyl bromide; (2-Bromo-5-chlorophenyl)bromomethane; 2-Bromo-5-chlorobenzyl bromide
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Bromomethyl-5-Chlorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.