Description

4-Bromophenyl Triflate is a high-purity organobromine and organosulfur reagent, specifically a phenyl trifluoromethanesulfonate derivative. This compound is valued for its role as a versatile electrophilic coupling partner and protecting group precursor in advanced synthetic chemistry. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require brominated aromatic scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized phosphine ligands or metal-organic frameworks (MOFs) with tailored properties.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers where the bromophenyl group modifies electronic properties.
• Chemical Biology Probes: Useful for labeling biomolecules or creating activity-based probes for proteomics and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses serving the fine chemical and life science sectors.

Basic Information

Item	Detail
Product Name	4-Bromophenyl Triflate
CAS No.	66107-30-0
Molecular Formula	C7H4BrF3O3S
Molecular Weight	305.07 g/mol
Synonyms	1-Bromo-4-[(trifluoromethyl)sulfonyl]oxy]benzene; p-Bromophenyl Trifluoromethanesulfonate; 4-Bromophenyl Trifluoromethanesulfonate; Trifluoromethanesulfonic Acid 4-Bromophenyl Ester; 4-Bromophenyl Triflate; 4-Bromo-1-(trifluoromethanesulfonyloxy)benzene; (4-Bromophenyl) Triflate
EINECS	Contact for details

Quality Control

Our 4-Bromophenyl Triflate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.