Description

4-Chloro-2,3-Dihydro-1H-Indene-1-Carboxylic Acid is a versatile indane derivative carboxylic acid that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its unique fused bicyclic structure with a carboxylic acid group and chlorine substituent makes it valuable for constructing complex molecular architectures. This compound is primarily sought after by pharmaceutical research and development teams, agrochemical manufacturers, and specialty chemical producers for applications in drug discovery, crop protection, and material science.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging its halogenated indane core.
• Ligand and Catalyst Development: Used to create novel chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Intermediate in the production of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Serves as a scaffold for developing enzyme inhibitors and molecular probes in biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for use in multi-step custom synthesis projects for clients.

Basic Information

Product Name	4-Chloro-2,3-Dihydro-1H-Indene-1-Carboxylic Acid
CAS No.	66041-25-6
Molecular Formula	C10H9ClO2
Molecular Weight	196.63 g/mol
Synonyms	4-Chloroindane-1-carboxylic Acid; 1H-Indene-1-carboxylic acid, 4-chloro-2,3-dihydro-; 4-Chloro-2,3-dihydro-1H-indene-1-carboxylic acid; 4-Chloro-1-indanecarboxylic Acid; 4-Chloroindan-1-carboxylic Acid; 66041-25-6; 4-Chloro-2,3-dihydroinden-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-2,3-Dihydro-1H-Indene-1-Carboxylic Acid is manufactured under strict quality management systems. We provide material with standard purity grades suitable for research and industrial synthesis, supported by comprehensive analytical documentation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch. Our quality commitment ensures consistency and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.