Description

Equol CAS NO 66036-38-2 is a biologically active isoflavandiol metabolite produced from the soy isoflavone daidzein by gut microbiota. Its significance lies in its potent and selective estrogenic activity, particularly as a high-affinity ligand for estrogen receptor beta (ERβ), which drives its role in various health and wellness applications. This compound is of primary interest to manufacturers in the nutraceutical, pharmaceutical, and cosmeceutical industries seeking to develop products targeting hormonal balance, bone health, and skin vitality.

Application

• Nutraceutical Formulations: Key ingredient in dietary supplements for menopausal symptom relief, bone density support, and cardiovascular health.
• Pharmaceutical Research: Active pharmaceutical ingredient (API) or intermediate in the development of selective estrogen receptor modulators (SERMs) and other hormone-related therapies.
• Cosmeceuticals: Incorporated into anti-aging skincare products for its potential to improve skin elasticity, hydration, and collagen synthesis.
• Functional Foods & Beverages: Used to fortify products aimed at promoting wellness through natural estrogenic pathways.
• Veterinary Applications: Employed in animal health supplements for similar endocrine-supporting benefits.
• Biochemical Research: Standard or reagent in laboratory studies investigating estrogen receptor signaling, metabolic pathways, and microbiome interactions.

Basic Information

Product Name	Equol
CAS No.	66036-38-2
Molecular Formula	C15H14O3
Molecular Weight	242.27 g/mol
Synonyms	(S)-Equol; (-)-Equol; 7-Hydroxy-3-(4'-hydroxyphenyl)-chroman; 4',7-Isoflavandiol; CI 2L; NSC 11364; S-Equol; (+/-)-Equol (racemic mixture); Daidzein metabolite
EINECS	Contact for details

Quality Control

Our Equol is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We offer grades suitable for research, nutraceutical, and pharmaceutical development, with specifications tailored to your application. Comprehensive quality testing, including identity, purity, and impurity profiling, is performed. Certificates of Analysis (COA) documenting compliance with agreed specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines
Loss on Drying	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.