Description

3-Benzylcyclobutanecarboxylic Acid is a versatile organic building block featuring a cyclobutane ring substituted with a benzyl group and a carboxylic acid functionality. This unique structure makes it a valuable intermediate for synthesizing complex molecules in pharmaceutical and agrochemical research. It is particularly sought after by R&D chemists and process development scientists for creating novel compounds with potential biological activity. The product is supplied under strict quality control to ensure batch-to-batch consistency for critical applications.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its constrained cyclobutane scaffold.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or metal-organic frameworks (MOFs) in asymmetric catalysis.
• Material Science: Building block for specialty polymers, liquid crystals, or organic electronic materials due to its rigid structure.
• Chemical Biology: Utilized in probe and linker synthesis for studying biological systems and protein interactions.
• Academic & Industrial R&D: Fundamental research reagent for exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	3-Benzylcyclobutanecarboxylic Acid
CAS No.	66016-21-5
Molecular Formula	C12H14O2
Molecular Weight	190.24 g/mol
Synonyms	3-Benzylcyclobutanecarboxylic Acid; Cyclobutanecarboxylic acid, 3-(phenylmethyl)-; 3-(Phenylmethyl)cyclobutanecarboxylic acid; 3-Benzyl-1-cyclobutanecarboxylic Acid; 66016-21-5; 3-Benzylcyclobutane-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Benzylcyclobutanecarboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its light-sensitive nature, prolonged exposure to direct light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.