Description

3-Propylcyclobutanecarboxylic Acid is a specialized cyclobutane derivative that serves as a valuable building block in advanced organic synthesis. Its unique strained-ring structure combined with a carboxylic acid functional group makes it a versatile intermediate for creating complex molecular architectures. This compound is primarily utilized by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and material science.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates requiring constrained, alicyclic frameworks.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides where the cyclobutane ring can influence biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or metal-organic frameworks (MOFs) in asymmetric catalysis and material science applications.
• Polymer & Material Science: Incorporated into specialty polymers to modify thermal properties, rigidity, or to create novel biodegradable materials.
• Chemical Research: Employed in academic and industrial laboratories for methodological studies in ring-strain chemistry and C–H functionalization.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing unique musk or amber odorants with specific stereochemical profiles.

Basic Information

Product Name	3-Propylcyclobutanecarboxylic Acid
CAS No.	66016-17-9
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	3-Propylcyclobutanecarboxylic Acid; Cyclobutanecarboxylic acid, 3-propyl-; 3-Propyl-1-cyclobutanecarboxylic acid; 3-n-Propylcyclobutanecarboxylic Acid; 66016-17-9; 3-propylcyclobutane-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Propylcyclobutanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.