Description

(-)-2-[(1E,3E)-1,3-Hexadienyl]-5-Methoxy-2-Methyl-4-[(E)-1-Oxo-2-Butenyl]Furan-3(2H)-One is a high-purity, optically active furanone derivative with a complex conjugated diene structure, making it a valuable chiral building block for advanced organic synthesis. Its unique molecular architecture is critical for constructing complex natural product analogs and bioactive molecules with specific stereochemistry. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control in their synthetic routes.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of potential drug candidates, particularly those targeting specific biological receptors.
• Agrochemical Research: Used in the development of novel, stereospecific pesticides and herbicides where the biological activity is highly dependent on molecular configuration.
• Fine Chemical Synthesis: Acts as a versatile precursor for fragrances, flavors, and other specialty chemicals requiring complex, unsaturated ring systems.
• Material Science Research: Investigated as a monomer or precursor for advanced polymers with specific optical or electronic properties due to its conjugated system.
• Academic & R&D: Employed in methodological studies and total synthesis projects for natural products and complex organic molecules.

Basic Information

Product Name	(-)-2-[(1E,3E)-1,3-Hexadienyl]-5-Methoxy-2-Methyl-4-[(E)-1-Oxo-2-Butenyl]Furan-3(2H)-One
CAS No.	65794-79-8
Molecular Formula	C18H22O4
Molecular Weight	302.37 g/mol
Synonyms	(-)-2-[(1E,3E)-1,3-Hexadien-1-yl]-5-methoxy-2-methyl-4-[(1E)-1-oxo-2-buten-1-yl]-3(2H)-furanone; (2S)-2-[(1E,3E)-Hexa-1,3-dien-1-yl]-5-methoxy-2-methyl-4-[(1E)-1-oxobut-2-en-1-yl]furan-3(2H)-one; Optically active furanone derivative; Chiral hexadienyl furanone; CAS 65794-79-8
EINECS	Contact for details

Quality Control

Our (-)-2-[(1E,3E)-1,3-Hexadienyl]-5-Methoxy-2-Methyl-4-[(E)-1-Oxo-2-Butenyl]Furan-3(2H)-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, chiral excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.