Description

n-(3-Fluoro-Phenyl)-Guanidine is a specialized guanidine derivative featuring a fluorine substituent on the phenyl ring, which significantly alters its electronic and physicochemical properties. This compound serves as a versatile and high-value building block in advanced organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate its unique fluorinated guanidine moiety into novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of bioactive molecules, including kinase inhibitors, receptor antagonists, and antiviral agents.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators that leverage the fluorine atom for enhanced activity and stability.
• Material Science Research: Used in the creation of specialty polymers, ligands for catalysis, and advanced organic frameworks (MOFs/COFs).
• Bioconjugation & Probe Development: Serves as a reactive handle for labeling biomolecules or creating fluorescent probes and diagnostic agents.
• Chemical Biology: Useful for studying enzyme mechanisms and protein interactions where the guanidine group mimics arginine side chains.

Basic Information

Item	Detail
Product Name	n-(3-Fluoro-Phenyl)-Guanidine
CAS No.	65783-19-9
Molecular Formula	C7H8FN3
Molecular Weight	153.16 g/mol
Synonyms	1-(3-Fluorophenyl)guanidine; 3-Fluorophenylguanidine; N-(3-Fluorophenyl)guanidine; Guanidine, N-(3-fluorophenyl)-; 1-(3-Fluorophenyl)guanidine hydrochloride (salt form); m-Fluorophenylguanidine; 3-F-C6H4-NH-C(=NH)NH2
EINECS	Contact for details

Quality Control

Our n-(3-Fluoro-Phenyl)-Guanidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.