Description

Silymarin is a standardized extract derived from the seeds of the milk thistle plant (*Silybum marianum*), primarily composed of flavonolignans including silybin, isosilybin, silychristin, and silydianin. This complex is highly valued for its potent hepatoprotective and antioxidant properties, making it a critical ingredient for supporting liver health and function. It is extensively utilized by manufacturers in the pharmaceutical, nutraceutical, and dietary supplement industries to formulate products aimed at liver detoxification, regeneration, and overall wellness support.

Application

• Pharmaceutical Formulations: Core active ingredient in prescription and over-the-counter (OTC) medicines for treating toxic liver damage, cirrhosis, and chronic inflammatory liver conditions.
• Dietary Supplements & Nutraceuticals: Key component in capsules, tablets, and liquid extracts marketed for liver support, detoxification, and antioxidant defense.
• Functional Food & Beverages: Incorporated into health drinks, fortified foods, and wellness shots designed to promote hepatic health.
• Cosmeceuticals: Used in topical skincare formulations for its anti-inflammatory and antioxidant benefits, helping to protect skin from environmental stressors.
• Veterinary Medicine: Employed in animal health products to support liver function in pets and livestock.
• Research & Development: Serves as a reference standard and active compound in pharmacological and clinical studies investigating hepatoprotection and flavonolignan activity.

Basic Information

Product Name	Silymarin
CAS No.	65666-07-1
Molecular Formula	Mixture (C25H22O10 for Silybin)
Molecular Weight	482.44 g/mol (for Silybin)
Synonyms	Milk Thistle Extract; Silybum marianum Extract; Legalon®; Silibinin; Flavonolignans from Silybum marianum; Carduus marianus extract; Marian thistle extract; Silymarin Group
EINECS	Contact for details

Quality Control

Our Silymarin is produced and tested to meet stringent quality standards appropriate for pharmaceutical and nutraceutical use. We offer various grades standardized to key flavonolignan content, typically 70-80% or higher, with silybin as a major marker. Production follows GMP (Good Manufacturing Practice) guidelines, and each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and safety parameters. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect stability and flow properties.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC/IR)	Complies with standard
Assay (Total Silymarin Flavonolignans)	70% - 80% (or as specified)
Assay (Silybin A+B)	≥ 30% (or as specified)
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals (as Pb)	≤ 10 ppm
Total Plate Count	≤ 1000 cfu/g
Yeast & Mold	≤ 100 cfu/g
E. Coli	Negative
Salmonella	Negative

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.