Description

7,8-Dimethoxyflavone is a synthetic derivative of the natural flavonoid class, specifically a dimethoxy-substituted flavone. This compound is valued for its role as a selective and potent positive allosteric modulator of the GABAA receptor, making it a critical research tool in neuroscience and pharmacology. It is primarily utilized by research institutions, pharmaceutical R&D departments, and nutraceutical developers investigating neuroprotection, cognitive enhancement, and anxiolytic pathways.

Application

• Neuroscience Research: Used as a selective positive allosteric modulator for studying GABAA receptor subtypes and their function in the central nervous system.
• Pharmacological R&D: Serves as a reference standard and lead compound in the development of novel anxiolytic, neuroprotective, and nootropic agents.
• Biochemical Assays: Employed in in vitro and cellular assays to investigate mechanisms of synaptic plasticity and neuronal excitability.
• Nutraceutical Research: Explored for potential applications in cognitive health and dietary supplement formulations targeting brain function.
• Academic Studies: A key reagent for university and institutional research into flavonoid bioactivity and receptor pharmacology.

Basic Information

Product Name	7,8-Dimethoxyflavone
CAS No.	65548-54-1
Molecular Formula	C17H14O4
Molecular Weight	282.29 g/mol
Synonyms	7,8-Dimethoxy-2-phenyl-4H-chromen-4-one; 7,8-Dimethoxy-2-phenyl-4H-1-benzopyran-4-one; 7,8-Dimethoxyflavone; DMFlavone; 7,8-DMF; GABAA receptor positive allosteric modulator; Flavone, 7,8-dimethoxy-
EINECS	Contact for details

Quality Control

Our 7,8-Dimethoxyflavone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.