Description

5-Chloromercurio-2'-Deoxyuridine is a specialized organomercury nucleoside analog of significant interest in biochemical and pharmaceutical research. This compound serves as a critical intermediate and a valuable tool for studying enzyme mechanisms, nucleic acid interactions, and as a potential precursor in the development of targeted therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in advanced molecular biology, antiviral research, and medicinal chemistry.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving thymidine kinase and other nucleoside-metabolizing enzymes.
• Antiviral Agent Development: Investigated as a precursor or analog in the synthesis of novel nucleoside-based antiviral compounds.
• Molecular Biology Tool: Acts as a probe for studying DNA-protein interactions and nucleic acid structure due to its mercury moiety, which can facilitate specific labeling or cleavage.
• Medicinal Chemistry Intermediate: Serves as a key building block for the synthesis of more complex molecules with potential therapeutic applications.
• Radiopharmaceutical Precursor: Can be utilized in the development of radiolabeled compounds for diagnostic imaging or targeted radiotherapy.

Basic Information

Product Name	5-Chloromercurio-2'-Deoxyuridine
CAS No.	65505-76-2
Molecular Formula	C9H11ClHgN2O5
Molecular Weight	447.25 g/mol
Synonyms	5-(Chloromercuri)-2'-deoxyuridine; 5-Chloromercuri-2'-deoxyuridine; 5-HgCl-2'-dUrd; 2'-Deoxy-5-(chloromercuri)uridine; 5-Chloromercurio-deoxyuridine; CldUrd-Hg; 5-(Chloromercurio)deoxyuridine; NSC 382180
EINECS	Contact for details

Quality Control

Our 5-Chloromercurio-2'-Deoxyuridine is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for research-grade chemicals, and specifications can be aligned with customer-specific requirements for advanced R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. Handle and store in accordance with all local regulations for mercury-containing compounds.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Heavy Metals (as Pb)	Contact for details
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.