Description

(2R-Trans)-2-(3,4-Dihydroxyphenyl)-3,4-Dihydro-3-Methoxy-2H-1-Benzopyran-5,7-Diol is a high-purity, stereochemically defined flavan derivative. This compound is valued for its role as a key intermediate in advanced pharmaceutical research and the synthesis of complex natural products. It is primarily sought by research institutions and manufacturers in the pharmaceutical, nutraceutical, and fine chemical sectors for its specific biological and chemical properties.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in studies of antioxidant mechanisms, enzyme inhibition, and cellular signaling pathways.
• Natural Product Synthesis: Serves as a precursor in the semi-synthesis or total synthesis of complex flavonoids and polyphenolic compounds.
• Nutraceutical Development: Investigated for potential inclusion in advanced dietary supplements targeting oxidative stress.
• Cosmeceutical Applications: Explored for use in high-end skincare formulations for its potential antioxidant properties.

Basic Information

Product Name	(2R-Trans)-2-(3,4-Dihydroxyphenyl)-3,4-Dihydro-3-Methoxy-2H-1-Benzopyran-5,7-Diol
CAS No.	65350-86-9
Molecular Formula	C16H16O6
Molecular Weight	304.29 g/mol
Synonyms	(2R,3R)-3',4',5,7-Tetrahydroxy-3-methoxyflavan; (2R,3R)-3-Methoxy-3',4',5,7-tetrahydroxyflavane; 3-Methoxy-3',4',5,7-tetrahydroxyflavan (2R,3R)-; Trans-(-)-3'-O-Methylcatechin; (-)-3'-O-Methylcatechin; (2R,3R)-3'-O-Methylcatechin; 3'-O-Methyl-(-)-catechin; Flavan-3-ol derivative
EINECS	Contact for details

Quality Control

Our (2R-Trans)-2-(3,4-Dihydroxyphenyl)-3,4-Dihydro-3-Methoxy-2H-1-Benzopyran-5,7-Diol is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). For long-term storage, consider storage under an inert gas such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (2R,3R)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.