Description

2-[(2-Chloroacetyl)(Methyl)Amino]Acetic Acid is a versatile bifunctional organic building block, primarily valued for its role as a key intermediate in the synthesis of complex molecules. Its structure, featuring both a chloroacetyl group and a carboxylic acid, makes it a critical reagent for introducing specific functional handles in pharmaceutical and agrochemical research. This compound is essential for manufacturers and R&D teams in the fine chemical, pharmaceutical, and life science sectors seeking to develop new active ingredients or modify peptide structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with peptide-like or amide backbones.
• Agrochemical Synthesis: Used in the development of novel herbicides, pesticides, and plant growth regulators that require specific chloroacetylated amino acid motifs.
• Peptide Chemistry & Modification: Serves as a reagent for the site-specific modification of peptides and proteins, enabling the attachment of labels, tags, or other functional groups.
• Chemical Biology & Proteomics: Employed in the design and synthesis of chemical probes and activity-based protein profiling (ABPP) reagents.
• Linker Molecule in Bioconjugation: Functions as a heterobifunctional crosslinker for coupling biomolecules due to its reactive chloro and carboxyl groups.
• Research & Development: A valuable tool for medicinal chemists and synthetic organic chemists exploring new chemical entities and reaction pathways.

Basic Information

Product Name	2-[(2-Chloroacetyl)(Methyl)Amino]Acetic Acid
CAS No.	65332-01-6
Molecular Formula	C5H8ClNO3
Molecular Weight	165.57 g/mol
Synonyms	N-(Carboxymethyl)-N-methyl-2-chloroacetamide; N-Methyl-N-(chloroacetyl)glycine; N-Methyliminodiacetic acid chloroacetyl ester; (Chloroacetyl)(methyl)aminoacetic acid; Chloroacetyl(methyl)aminoacetic acid; N-Methyl-N-(chloroacetyl)aminoacetic acid; 2-[Methyl(chloroacetyl)amino]acetic acid; Glycine, N-(chloroacetyl)-N-methyl-
EINECS	Contact for details

Quality Control

Our 2-[(2-Chloroacetyl)(Methyl)Amino]Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of our global clientele in advanced synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.