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3-Iodopyridazine CAS NO 65202-53-1
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CAS No.:65202-53-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Iodopyridazine is a versatile halogenated heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in enabling the efficient construction of complex molecular architectures through cross-coupling reactions and nucleophilic substitutions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it serves as a key precursor for active pharmaceutical ingredients (APIs), functional ligands, and advanced organic materials.
Application
- Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
- Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
- Material Science Precursor: Employed in the creation of organic electronic materials, such as ligands for OLEDs and charge-transport molecules.
- Cross-Coupling Reactions: Serves as a reliable substrate for Suzuki-Miyaura, Stille, and Sonogashira couplings to introduce the pyridazine moiety into complex systems.
- Nucleophilic Substitution: The iodine atom is readily displaced, allowing for functionalization with various nucleophiles to create diverse chemical libraries.
- Ligand Synthesis: Used to prepare specialized ligands for catalysis and metal-organic frameworks (MOFs).
- Chemical Biology Probes: Acts as a starting point for synthesizing molecular probes and tags for biochemical research.
Basic Information
| Item | Details |
|---|---|
| Product Name | 3-Iodopyridazine |
| CAS No. | 65202-53-1 |
| Molecular Formula | C4H3IN2 |
| Molecular Weight | 205.98 g/mol |
| Synonyms | 3-Iodopyridazine; Pyridazine, 3-iodo-; Iodopyridazine; 3IPD; 3-Pyridazinyl iodide; 65202-53-1; 3-Iodo-1,2-diazine |
| EINECS | Contact for details |
Quality Control
Our 3-Iodopyridazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and GC-MS for impurity profiling, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specifications and test results.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling under subdued light is recommended for long-term stability.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Heavy Metals | < 10 ppm |
| Residual Solvents (GC) | Complies with ICH guidelines |
| Water Content (KF) | < 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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