Description

Avermectin B1B CAS NO 65195-56-4 is a potent macrocyclic lactone derivative belonging to the avermectin family, renowned for its exceptional anthelmintic and insecticidal activity. This high-purity compound is a critical active pharmaceutical ingredient (API) and agrochemical intermediate, valued for its efficacy and specificity. It is essential for manufacturers in the pharmaceutical and agricultural sectors developing advanced veterinary parasiticide formulations and crop protection products.

Application

• Active Pharmaceutical Ingredient (API) in veterinary anthelmintic injections and pour-on solutions.
• Key intermediate in the synthesis of more potent derivatives like Doramectin.
• Core component in agricultural insecticides and acaricides for high-value crops.
• Research and development of novel parasitic control agents in animal health.
• Formulation of endectocides for livestock (cattle, sheep, swine).
• Manufacturing of pest control products for horticulture and turf management.

Basic Information

Product Name	Avermectin B1B
CAS No.	65195-56-4
Molecular Formula	C48H72O14
Molecular Weight	873.1 g/mol
Synonyms	Abamectin B1B; Avermectin B1b; 5-O-Demethylavermectin A1b; MK-0936 component B1b; (10E,14E,16E)-(1R,4S,5'S,6R,6'R,8R,12S,13S,20R,21R,24S)-6'-[(S)-sec-Butyl]-21,24-dihydroxy-5',11,13,22-tetramethyl-2-oxo-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6-spiro-2'-(5',6'-dihydro-2'H-pyran)-12-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-3-O-methyl-α-L-arabino-hexopyranoside
EINECS	Contact for details

Quality Control

Our Avermectin B1B is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and related substances, to ensure it meets stringent specifications for pharmaceutical and agrochemical use. Certificates of Analysis (COA) are provided with every shipment, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.