Description

Avermectin B1A CAS NO 65195-55-3 is a major component of the naturally occurring macrocyclic lactone insecticide and acaricide, Avermectin B1. This compound is valued for its exceptional potency and broad-spectrum activity against a wide range of agricultural pests and parasites. It is a critical active ingredient and intermediate for manufacturers in the agrochemical and veterinary pharmaceutical industries, serving as the foundation for producing more potent derivatives like emamectin benzoate.

Application

• Agrochemical Intermediate: Primary use as a key starting material for the synthesis of advanced insecticides such as emamectin benzoate and abamectin.
• Crop Protection Formulations: Used in the development of concentrated solutions and emulsifiable concentrates for controlling mites, leaf miners, and other pests on fruits, vegetables, and ornamental plants.
• Veterinary Pharmaceutical Ingredient: Serves as an active pharmaceutical ingredient (API) in formulations for parasiticides targeting internal and external parasites in livestock and companion animals.
• Research & Development: Utilized as a high-purity reference standard in analytical laboratories for method development, quality control, and residue analysis.
• Biopesticide Production: Acts as a core component in the manufacture of environmentally friendly, bio-based pesticide products.

Basic Information

Product Name	Avermectin B1A
CAS No.	65195-55-3
Molecular Formula	C48H72O14
Molecular Weight	873.1 g/mol
Synonyms	Avermectin B1a; Avermectin A1a; 5-O-Demethylavermectin A1a; Abamectin B1a; MK-0936; C076; (10E,14E,16E)-(1R,4S,5'S,6R,6'R,8R,12S,13S,20R,21R,24S)-6'-[(S)-sec-butyl]-21,24-dihydroxy-5',11,13,22-tetramethyl-2-oxo-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6-spiro-2'-(5',6'-dihydro-2'H-pyran)-12-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-3-O-methyl-α-L-arabino-hexopyranoside
EINECS	Contact for details

Quality Control

Our Avermectin B1A is produced and tested under strict quality management systems. Each batch undergoes comprehensive analysis to ensure identity, purity, and consistency, meeting the stringent requirements for use in pharmaceutical and agrochemical synthesis. A Certificate of Analysis (COA) detailing specific test results, including assay by HPLC and related substance profiles, is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider holding under inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 92.0% (Avermectin B1a)
Related Substances (HPLC)	Avermectin B1b: ≤ 5.0% Total other impurities: ≤ 3.0% Any single unknown impurity: ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.