Description

(23S)-22,23-Dihydro-23-Hydroxyavermectin A1A is a key semi-synthetic derivative of the naturally occurring macrocyclic lactone, avermectin. This compound is valued for its potent biological activity and serves as a crucial intermediate in the synthesis of advanced pharmaceutical and agrochemical agents. It is primarily required by manufacturers in the pharmaceutical industry for developing antiparasitic drugs and by agrochemical companies for creating next-generation crop protection products.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel antiparasitic and anthelmintic medications.
• Agrochemical Research & Development: Used in the development of high-efficacy insecticides and acaricides for crop protection.
• Veterinary Medicine: Serves as a precursor in the formulation of treatments for parasitic infections in livestock and companion animals.
• Biochemical Research: Employed as a reference standard and active agent in studies of ion channel function and neuropharmacology.
• Active Pharmaceutical Ingredient (API) Synthesis: Integral to the manufacturing process of bulk APIs for finished dosage forms.

Basic Information

Product Name	(23S)-22,23-Dihydro-23-Hydroxyavermectin A1A
CAS No.	65195-53-1
Molecular Formula	C48H72O15
Molecular Weight	889.08 g/mol
Synonyms	22,23-Dihydroavermectin B1a; 22,23-Dihydro-23-hydroxy-avermectin A1A; Avermectin B1a, 22,23-dihydro-23-hydroxy-; 23-Hydroxy-22,23-dihydroavermectin A1A; 23-Hydroxy-22,23-dihydroavermectin B1a; 23-Hydroxy-22,23-dihydro-13-deoxy-25-de(1-methylpropyl)-25-(1-methylethyl)avermectin A1a; (23S)-22,23-Dihydro-23-hydroxy-avermectin A1A
EINECS	Contact for details

Quality Control

Our (23S)-22,23-Dihydro-23-Hydroxyavermectin A1A is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and agrochemical synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.