Description

25-De(1-Methylpropyl)-25-(1-Methylethyl)Avermectin A1A is a semi-synthetic derivative of the naturally occurring avermectin family of macrocyclic lactones. This compound is valued for its potent biological activity and serves as a crucial intermediate in the development of advanced agrochemicals and veterinary pharmaceuticals. It is primarily sought by research institutions and manufacturers in the agrochemical and animal health industries for the synthesis of next-generation parasiticides and insecticides.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel, high-efficacy acaricides and insecticides for crop protection.
• Veterinary Pharmaceutical Research: Used in the development of new endectocide formulations for livestock and companion animals.
• Biochemical Research: Serves as a reference standard and active ingredient in studies targeting glutamate-gated chloride channels in invertebrates.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the manufacturing process for specialized antiparasitic drugs.

Basic Information

Product Name	25-De(1-Methylpropyl)-25-(1-Methylethyl)Avermectin A1A
CAS No.	65195-52-0
Molecular Formula	C₄₈H₇₂O₁₄
Molecular Weight	873.1 g/mol
Synonyms	25-De(1-Methylpropyl)-25-(1-Methylethyl)Avermectin A1A; 4"-Deoxy-4"-(methylamino)avermectin B1a; MK-0244; Emamectin Benzoate Intermediate; 4"-Epimethylamino-4"-deoxyavermectin B1a; Avermectin A1a, 25-de(1-methylpropyl)-25-(1-methylethyl)-; (10E,14E,16E)-(1R,4S,5'S,6R,6'R,8R,12S,13S,20R,21R,24S)-6'-[(S)-sec-butyl]-21,24-dihydroxy-5',11,13,22-tetramethyl-2-oxo-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6-spiro-2'-(5',6'-dihydro-2'H-pyran)-12-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-3-O-methyl-α-L-arabino-hexopyranoside
EINECS	Contact for details

Quality Control

Our 25-De(1-Methylpropyl)-25-(1-Methylethyl)Avermectin A1A is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise specifications for research and synthesis purposes. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.