Description

2-Chloro-4-Bromoethylbenzene is a versatile halogenated aromatic intermediate of significant importance in advanced organic synthesis. Its value lies in the strategic positioning of chlorine and bromine substituents on the ethylbenzene ring, which allows for selective functionalization and the construction of complex molecular architectures. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as active pharmaceutical ingredient (API) synthesis and the development of novel materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring halogenated aromatic cores for bioactivity or further derivatization.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides, where the halogen atoms serve as points for further chemical modification.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of liquid crystals, organic semiconductors, and polymers with specific electronic or optical properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) due to the differential reactivity of the C-Cl and C-Br bonds.
• Fine Chemical Manufacturing: Acts as a critical intermediate in the multi-step synthesis of dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	2-Chloro-4-Bromoethylbenzene
CAS No.	65130-47-4
Molecular Formula	C8H8BrCl
Molecular Weight	219.51 g/mol
Synonyms	1-Bromo-4-chloro-2-ethylbenzene; 4-Bromo-2-chloroethylbenzene; 2-Chloro-1-bromo-4-ethylbenzene; 2-Chloro-4-bromo-1-ethylbenzene; (2-Chloro-4-bromophenyl)ethane; Ethylbenzene, 2-chloro-4-bromo-; 2-Ethyl-5-bromochlorobenzene; 4-Bromo-2-chloro-1-ethylbenzene
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Bromoethylbenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is 2-25°C. The compound is soluble in organic solvents; ensure containers are kept upright to prevent leakage.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.