Description

7-Acetyl-1-Chloro-10-(3-Dimethylaminopropyl)-10H-Pyridazino[4,5-B][1,4]Benzoxazine is a sophisticated heterocyclic organic compound that serves as a critical advanced intermediate in modern pharmaceutical synthesis. Its complex fused-ring structure, featuring acetyl, chloro, and dimethylaminopropyl substituents, makes it a valuable building block for developing novel active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research and production in medicinal chemistry, particularly for targeting central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel psychotropic and neuroactive drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold in the multi-step synthesis of complex target molecules.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development.
• Preclinical & Clinical Trial Material Production: Manufactured under controlled conditions to support the development of new drug entities.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical labs.

Basic Information

Product Name	7-Acetyl-1-Chloro-10-(3-Dimethylaminopropyl)-10H-Pyridazino[4,5-B][1,4]Benzoxazine
CAS No.	64610-62-4
Molecular Formula	C₁₉H₂₁ClN₄O₂
Molecular Weight	372.85 g/mol
Synonyms	1-Chloro-7-acetyl-10-(3-dimethylaminopropyl)-10H-pyridazino[4,5-b][1,4]benzoxazine; 10H-Pyridazino[4,5-b][1,4]benzoxazine, 7-acetyl-1-chloro-10-[3-(dimethylamino)propyl]-; 64610-62-4; Pyridazinobenzoxazine derivative; 7-Acetyl-1-chloro-10-(3-dimethylaminopropyl)pyridazino[4,5-b][1,4]benzoxazine
EINECS	Contact for details

Quality Control

Our 7-Acetyl-1-Chloro-10-(3-Dimethylaminopropyl)-10H-Pyridazino[4,5-B][1,4]Benzoxazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). The compound may be light-sensitive and hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.