Description

n-(4-Nitrophenylsulfonyl)-L-Phenylalanine is a specialized, optically active sulfonamide derivative of the amino acid L-phenylalanine. This compound matters as a high-value chiral building block and intermediate, crucial for the synthesis of complex molecules where stereochemical integrity is paramount. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of peptide-based therapeutics, enzyme inhibitors, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for protease inhibitors and other peptide mimetics.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate protease activity and specificity.
• Peptide Chemistry: Serves as a protected or modified amino acid derivative in solid-phase and solution-phase peptide synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of activity-based probes for labeling and studying biological targets.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in stereoselective organic synthesis.
• Reference Standard: Sourced for analytical purposes as a high-purity standard for quality control and method development in laboratories.

Basic Information

Product Name	n-(4-Nitrophenylsulfonyl)-L-Phenylalanine
CAS No.	64501-87-7
Molecular Formula	C15H14N2O6S
Molecular Weight	350.35 g/mol
Synonyms	N-(4-Nitrobenzenesulfonyl)-L-phenylalanine; L-Phenylalanine, N-[(4-nitrophenyl)sulfonyl]-; 4-Nitrobenzenesulfonyl-L-phenylalanine; (S)-2-((4-Nitrobenzenesulfonamido)-3-phenylpropanoic acid; N-4-Nitrobenzenesulfonyl-L-phenylalanine; N-(p-Nitrobenzenesulfonyl)-L-phenylalanine; N-(4-Nitrophenylsulfonyl)-L-Phe-OH; N-Phenylalanine-4-nitrobenzenesulfonamide
EINECS	Contact for details

Quality Control

Our n-(4-Nitrophenylsulfonyl)-L-Phenylalanine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and chiral integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.