Description

1,4,7,10-Tetraoxacyclododecane is a versatile macrocyclic polyether, commonly known as 12-crown-4, which functions as a highly effective phase-transfer catalyst and complexing agent. Its primary value lies in its ability to selectively bind alkali metal cations, particularly lithium ions, making it indispensable for applications requiring precise ion separation or transport. This compound is critically needed by researchers and manufacturers in the pharmaceutical, battery technology, and specialty chemical synthesis sectors for developing advanced materials and processes.

Application

• Lithium-Ion Battery Electrolytes: As a key additive to enhance lithium-ion conductivity and stabilize the solid-electrolyte interphase (SEI) layer in advanced battery formulations.
• Phase-Transfer Catalysis (PTC): Facilitates reactions between reagents in immiscible phases, crucial for organic synthesis in pharmaceutical and fine chemical manufacturing.
• Chemical Sensors & Extraction: Serves as a selective ionophore in sensor membranes for lithium detection and in separation processes for metal ion recovery.
• Polymer & Material Science: Used as a building block or templating agent in the synthesis of functional polymers and nanostructured materials.
• Academic & Industrial Research: A fundamental reagent for studying cation-macrocycle interactions and developing new catalytic systems.

Basic Information

Product Name	1,4,7,10-Tetraoxacyclododecane
CAS No.	64491-37-8
Molecular Formula	C8H16O4
Molecular Weight	176.21 g/mol
Synonyms	12-Crown-4; 1,4,7,10-Tetraoxacyclododecane; 12-Crown-4 ether; 1,4,7,10-Tetraoxacyclododecane, 12-crown-4; Dodecahydrodibenzo[b,f][1,4,7,10]tetraoxacyclododecine (related structure); Lithium ionophore I; Crown ether 12C4
EINECS	Contact for details

Quality Control

Our 1,4,7,10-Tetraoxacyclododecane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.