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2-[2-[4-(Diethylamino)Phenyl]Vinyl]-1,3,3-Trimethyl-3H-Indolium Acetate CAS NO 64346-30-1


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CAS No.:64346-30-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-[2-[4-(Diethylamino)Phenyl]Vinyl]-1,3,3-Trimethyl-3H-Indolium Acetate is a high-purity organic salt belonging to the cyanine dye family, specifically a heptamethine cyanine derivative. This compound matters for its exceptional performance as a near-infrared (NIR) fluorescent probe and photosensitizer, offering critical functionality in advanced diagnostic and research applications. It is primarily needed by manufacturers and research institutions in the biotechnology, medical diagnostics, and pharmaceutical development sectors.

Application

  • Fluorescent Labeling Agent: Used as a NIR fluorescent tag for biomolecules (proteins, antibodies, nucleic acids) in immunoassays and flow cytometry.
  • Bioimaging Probe: Employed in the development of contrast agents for in vivo and in vitro imaging due to its deep tissue penetration and low background interference.
  • Photodynamic Therapy (PDT): Serves as a potential photosensitizer in cancer treatment research, generating reactive oxygen species upon light activation.
  • Optical Sensor Development: A key component in creating chemical sensors and biosensors for detecting specific ions or biological targets.
  • Material Science: Used in the synthesis of functional dyes for non-linear optics and as a dopant in advanced polymeric materials.
  • Research & Development: A vital reagent in academic and industrial R&D for studying biological processes, drug delivery mechanisms, and photochemical reactions.

Basic Information

Product Name 2-[2-[4-(Diethylamino)Phenyl]Vinyl]-1,3,3-Trimethyl-3H-Indolium Acetate
CAS No. 64346-30-1
Molecular Formula C26H32N2O2
Molecular Weight 404.55 g/mol
Synonyms IR-780 Iodide Analog (Acetate Salt); Heptamethine Cyanine Dye Acetate; 1,3,3-Trimethyl-2-[2-[4-(diethylamino)phenyl]ethenyl]-3H-indolium acetate; Cy7.5 dye derivative; NIR-797 related compound; 3H-Indolium, 2-[2-[4-(diethylamino)phenyl]ethenyl]-1,3,3-trimethyl-, acetate (1:1); 2-[2-[4-(Diethylamino)styryl]-1,3,3-trimethyl-3H-indolium acetate
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Quality Control

Our 2-[2-[4-(Diethylamino)Phenyl]Vinyl]-1,3,3-Trimethyl-3H-Indolium Acetate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and spectrophotometry for optical property verification. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. Due to its hygroscopic nature, the container should be kept in a desiccated environment. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance Dark green to blue-black crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.5%
Absorption Max (λmax) 780 - 800 nm (in methanol)
Emission Max (λem) 805 - 825 nm (in methanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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