Description

(S)-Dihydro-4-Methylfuran-2(3H)-One is a high-value chiral lactone building block essential for asymmetric synthesis. Its defined stereochemistry provides a critical advantage in the production of enantiomerically pure pharmaceuticals and fine chemicals, ensuring superior efficacy and reducing unwanted side effects. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where the specific stereoisomer can significantly influence biological activity and environmental safety.
• Flavor and Fragrance Industry: Serves as a precursor for lactone-based flavoring agents and aroma chemicals, contributing to complex, natural-tasting profiles.
• Asymmetric Catalysis Research: Employed as a standard substrate or ligand precursor in academic and industrial research to develop and test new chiral catalysts and methodologies.
• Polymer Chemistry: Acts as a monomer or co-monomer for synthesizing specialized biodegradable or functional polymers with tailored properties.
• Fine Chemical Production: Utilized in multi-step syntheses of complex natural products, advanced materials, and other high-value specialty chemicals.

Basic Information

Product Name	(S)-Dihydro-4-Methylfuran-2(3H)-One
CAS No.	64190-48-3
Molecular Formula	C5H8O2
Molecular Weight	100.12 g/mol
Synonyms	(S)-4-Methyl-γ-butyrolactone; (S)-4-Methylbutyrolactone; (S)-4-Methyldihydrofuran-2(3H)-one; (S)-4-Methyl-γ-lactone; (S)-4-Methyloxolan-2-one; (S)-Pantolactone (less common); (S)-(-)-4-Methylbutyrolactone; (S)-(-)-4-Methyl-γ-butyrolactone
EINECS	Contact for details

Quality Control

Our (S)-Dihydro-4-Methylfuran-2(3H)-One is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for sensitive asymmetric synthesis. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to strong bases and organic solvents, and because it is easily oxidized, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation to maintain optimal purity and chiral integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.