Description

1-Tributylstannyl-3,3,3-trifluoro-1-propyne is a specialized organotin reagent featuring a reactive trifluoromethylated alkyne moiety. This compound is valued for its role as a versatile building block in advanced organic synthesis, particularly for introducing fluorinated carbon frameworks. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, leveraging the trifluoromethyl group to enhance metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in constructing active ingredients for crop protection agents, where the fluorine atoms can improve biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for developing fluorinated polymers, liquid crystals, or advanced coatings with unique surface properties.
• Cross-Coupling Reactions: Acts as a stamane coupling partner in Stille-type reactions to form carbon-carbon bonds with aryl or vinyl halides.
• Ligand and Catalyst Development: Employed in the preparation of novel organometallic complexes and catalysts for specialized chemical transformations.
• Fluorine Chemistry Studies: A valuable reagent for academic and industrial research focused on the synthesis and reactivity of fluoroorganic compounds.

Basic Information

Product Name	1-Tributylstannyl-3,3,3-trifluoro-1-propyne
CAS No.	64185-12-2
Molecular Formula	C15H27F3Sn
Molecular Weight	375.07 g/mol
Synonyms	3,3,3-Trifluoro-1-(tributylstannyl)-1-propyne; Tributyl(3,3,3-trifluoroprop-1-yn-1-yl)stannane; 3,3,3-Trifluoroprop-1-yn-1-yltributylstannane; (3,3,3-Trifluoroprop-1-ynyl)tributyltin; Tributylstannyl trifluoromethylacetylene; 1-Tributylstannyl-3,3,3-trifluoropropyne; TBTCFPA
EINECS	Contact for details

Quality Control

Our production of 1-Tributylstannyl-3,3,3-trifluoro-1-propyne adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by standard analytical techniques including NMR, GC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place (recommended 2-8°C or as specified on the label). This material is moisture-sensitive and easily oxidized; ensure containers are sealed immediately after use to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 95% (typical 97-99%)
Tin (Sn) Content	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.